AAPE® Stem Cell Therapy

Our skin is shaped by collagen by the collagen produced organically in our bodies and a loss in collagen causes a number of undesirable skin issues as we age. The skin often becomes loose due to the gravity pull resulting from collagen loss in the body. With age, reduced collagen also leads to thinner skin, reducing the skin’s ability to retain moisture (Hyaluronic acid) and elasticity (from elastin). Wrinkles, hollowed cheeks, dry/rough skin with dark spots, sagging eyelids, and bags under the eyes became challenging issues for the human body once collagen gets lowered below a specific limit. We begin to lose about 1% of collagen every year over the age of 20. Collagen loss is accelerated by sun exposure, tobacco, excessive sugar and cortisol from stress.

FDA approved AAPE® for skin rejuvenation induces glutathione peroxidase activity and increases fibroblast proliferation. AAPE® therapy (approx. 3-6 treatments) can effectively increase dermal thickness (by 30%), remove wrinkles (by 47.4%), heal wounds/scarring, lighten the skin and cause antioxidant effects. AAPE® replaces the facial volume lost with age and helps skin rejuvenate by skin repair from inside out. Here’s how…

AAPE® holds a distinct blend profile that is engineered to maximize one’s skin revitalizing effects. It is a mixture of cytokine proteins and refined growth factors obtained from the conditioned media that cultures the human ADSC (Adipose-Derived Stem Cells). ADSC are stem cells derived from adipose. Stem cells are primarily primordial cells that hold the potential ability to differentiate after evolution into a broad range of specialized cell types and species. These cells can be observed working in all multi-cellular organisms and most of their tissues. As opposed to meiosis, mitosis (simple cell division) occurs when stem cells perpetuate themselves due to their evolving capabilities.

AAPE® employs Stem Cells therapy to the fullest by acting as protein messengers to change, rearrange, or repair the local tissues rapidly and significantly by extracting from stem cells. This stem cell therapy helps damaged or aged skin cells restore their embryonic potential. The therapy also aims to develop the aging tissues as the exosomes from stem cells derived from human adipose promote the migration and proliferation of skin fibroblasts.

AAPE® is comprised of extracellular matrix proteins as well as the extracted and purified growth factor proteins. The growth factors, along with robust regenerative stem and stromal cells, biologic components, and progenitor cells, help the cells to regenerate growth. Stromal vascular fraction (SVF) holds these regenerative elements, coupled with mesenchymal stem cells. AAPE® serum’s fat tissue or adipose provides a combination of a considerable quantity of mesenchymal stem cells and other powerful components in the SVF to catalyze the regenerative process.

AAPE® for Skin Rejuvenation is an innovative cellular treatment that originated from the most advanced cellular science. The therapy helps maximize the skin’s revitalizing effects due to natural capabilities for regeneration and synergic action. The stem cells applied to skin rejuvenation via AAPE® serum are the protein extract of human adipose tissue containing more than 300 growth factors that help reduce aging and produce anti-wrinkles effects. The factors include vascular endothelial, insulin-like growth factor 1, hepatocyte, platelet-derived growth factor, etc. the protein extracts in the stem cells also contribute by delivering superior biological activity that improves skin elasticity and boosts cell repair process. Scientific research has proven AAPE® to be an effective, safe, and powerful treatment for anti-aging skincare due to its extraction from human adipose-derived stem cells.

Multiple stem cell products like AAPE® were developed due to recent progressive technologies and techniques like cell culture and cultivation, protein extraction, and purification. All the recent advances in stem cells have been possible due to a chance discovery that fatty tissue like adipose in the human body holds the single most concentration of stem cells. AAPE® is set to revolutionize the cosmetic industry.

  • AAPE® is the first product based on stem cell described in SCI journals with clinical results in humans.
  • Exosomes from human adipose derived stem cells promote proliferation and migration of skin fibroblasts.
  • AAPE® has over 600,000 clinical treatments used by over 3,000 dermatologists in more than 30 countries worldwide.
  • US FDA Approval
  • PCPC US registration
  • No adverse side effects or risks that Platelet-Rich Plasma, aka PRP or “Vampire Facial”, carries (Risks include injury to blood vessels or nerves, infection, calcification at the injection points, scar tissue build up and negative reactions associated with the anesthetic used)
  • Adipose-derived stem cell-conditioned medium containing more than 300 growth factors such as vascular endothelial growth factor, hepatocyte growth factor, platelet-derived growth factor, and insulin-like growth factor 1 (PRP only contains 10-15 growth factors)